Workshops

Overview

The workshop will provide an in-depth overview of the clinical and diagnostic applications of molecular cytogenetics, with a particular focus on fluorescence in situ hybridization (FISH) in haematological malignancies. Participants will be introduced to the principles of FISH, including its role in detecting chromosomal abnormalities such as gene rearrangements, amplifications, and deletions that are critical in the diagnosis, prognosis, and management of blood cancers. 

The session will highlight how FISH integrates into the broader diagnostic workflow alongside morphology, immunohistochemistry, and molecular techniques such as PCR and sequencing. Emphasis will be placed on the interpretation of common FISH signal patterns and their clinical relevance in diseases such as leukemia and lymphoma. 

A key aspect of the discussion will be the comparative value of FISH in relation to other diagnostic methods, particularly its sensitivity, specificity, and utility in resolving equivocal cases. The workshop will also explore how molecular cytogenetics supports precision medicine by guiding targeted therapy decisions and improving patient outcomes. Overall, the workshop will strengthen participants’ understanding of FISH as a powerful tool in modern haematology and its growing importance in clinical decision-making and research applications.ns.